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Saturday, December 21, 2024

Bortree Lecture Series - Ganesh Anand- Talk Title: “Virus Breathing, Metastability and Epitope Dynamics by Integrative Mass Spectrometry” on November 16, 2022

Ganesh Anand, PhD Associate Professor of Chemistry, and Biochemistry and Molecular Biology

When: November 16, 2022, 11:00 AM - 12:00 PM

Where: 106 AVBS Building

Contact: Margaret Weber

Contact Phone: 814-865-7697

Web: Visit external website

The Anand research group’s interests are in uncovering dynamics of cellular macromolecular assemblies. Focus areas include whole viral particle dynamics, capsid metastability and viral host entry, Second messenger (cyclic nucelotide) signaling and regulation, Transmembrane signaling and Two-component signal transduction. Our primary tool to probe protein dynamics is structural mass spectrometry (MS) and includes amide hydrogen/deuterium exchange mass spectrometry (HDX-MS), ion mobility mass spectrometry (IM-MS), cross-linking, native MS together with proteomics and biophysical approaches. Allostery forms a common theme of our research and our goal is to integrate protein dynamics with biochemistry.

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